7-Deaza-2′-deoxyguanosine 5′-triphosphate

更新时间:2024-01-14 06:52:42

7-Deaza-2′-deoxyguanosine 5′-triphosphate结构式
7-Deaza-2′-deoxyguanosine 5′-triphosphate结构式
品牌特惠专场
常用名 7-Deaza-2′-deoxyguanosine 5′-triphosphate 英文名 7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS号 101515-08-6 分子量 512.12600
密度 2.48 g/cm3 沸点 907.1ºC at 760 mmHg
分子式 C11H16LiN4O13P3 熔点 N/A
MSDS 美版 闪点 502.4ºC

 用途


7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP) 是一种核苷酸类似物,是一种端粒酶抑制剂 (IC50: 11μM)。

 名称

英文名 [[5-(2-amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
英文别名 更多

 生物活性

描述 7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP) 是一种核苷酸类似物,是一种端粒酶抑制剂 (IC50: 11μM)。
相关类别
参考文献

[1]. Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35(49):15611-7.  

 物理化学性质

密度 2.48 g/cm3
沸点 907.1ºC at 760 mmHg
分子式 C11H16LiN4O13P3
分子量 512.12600
闪点 502.4ºC
精确质量 512.00900
PSA 298.24000
LogP 0.31790
蒸汽压 1.76E-35mmHg at 25°C
折射率 1.854

 安全信息

危险品运输编码 NONH for all modes of transport

 文献53

更多文献
Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.

Neurosci. Lett. 590 , 116-20, (2015)

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET182C) polymorphisms are associated with susceptibility and treatment response in major depressive disorder (MDD). Thus, we examined ...

5-HTTLPR genotype, asthma, diabetes and late-life depression in an older French population.

Int. J. Geriatr. Psychiatry 30 , 1017-22, (2015)

Associations between environmental risk factors and depression have been reported to be stronger in people with the S allele of the S/L polymorphism in the serotonin transporter gene-linked promoter r...

Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.

Amyotroph. Lateral Scler. Frontotemporal Degener. 15(7-8) , 569-80, (2014)

Our objective was to present clinicopathologic evidence of anterior visual pathway involvement in patients with amyotrophic lateral sclerosis (ALS) secondary to a C9orf72 mutation. Two related patient...

 英文别名

7-Deaza-2 inverted exclamation marka-deoxyguanosine 5 inverted exclamation marka-triphosphate lithium salt
7-Deaza-dGTP