β-Estradiol-6-one 6-(O-carboxymethyloxime)结构式
|
常用名 | β-Estradiol-6-one 6-(O-carboxymethyloxime) | 英文名 | β-Estradiol-6-one 6-(O-carboxymethyloxime) |
---|---|---|---|---|
CAS号 | 35048-47-6 | 分子量 | 359.416 | |
密度 | 1.5±0.1 g/cm3 | 沸点 | 572.6±60.0 °C at 760 mmHg | |
分子式 | C20H25NO5 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | 300.1±32.9 °C |
用途β-Estradiol-6-one 6-(O-carboxymethyloxime) 是一种 PROTAC linker,属于 alkyl chain 类。可用于合成 PROTAC 分子。 |
英文名 | 17β-estradiol 6-O-(carboxymethyl)oxime |
---|---|
英文别名 | 更多 |
描述 | β-Estradiol-6-one 6-(O-carboxymethyloxime) 是一种 PROTAC linker,属于 alkyl chain 类。可用于合成 PROTAC 分子。 |
---|---|
相关类别 | |
靶点 |
Alkyl-Chain |
体外研究 | PROTACs包含两种不同的配体,它们通过连接体连接;一种是E3泛素连接酶的配体,另一种是靶蛋白的配体。PROTACs利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白[1]。 |
参考文献 |
密度 | 1.5±0.1 g/cm3 |
---|---|
沸点 | 572.6±60.0 °C at 760 mmHg |
分子式 | C20H25NO5 |
分子量 | 359.416 |
闪点 | 300.1±32.9 °C |
精确质量 | 359.173279 |
PSA | 99.35000 |
LogP | 2.31 |
蒸汽压 | 0.0±1.7 mmHg at 25°C |
折射率 | 1.680 |
储存条件 | 2-8°C,密封,干燥 |
个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
安全声明 (欧洲) | 22-24/25 |
危险品运输编码 | NONH for all modes of transport |
~% β-Estradiol-6-o... 35048-47-6 |
文献:Steroids, , vol. 19, # 4 p. 509 - 518 |
~% β-Estradiol-6-o... 35048-47-6 |
文献:Steroids, , vol. 18, p. 593 - 603 |
~% β-Estradiol-6-o... 35048-47-6 |
文献:Steroids, , vol. 18, p. 593 - 603 |
~% β-Estradiol-6-o... 35048-47-6 |
文献:Steroids, , vol. 30, # 1 p. 85 - 98 |
~% β-Estradiol-6-o... 35048-47-6 |
文献:Steroids, , vol. 21, p. 259 - 283 |
~% β-Estradiol-6-o... 35048-47-6 |
文献:Steroids, , vol. 21, p. 259 - 283 |
A convenient homogeneous enzyme immunoassay for estradiol detection.
Biotechnol. Appl. Biochem. 58(1) , 75-82, (2011) A convenient homogeneous enzyme immunoassay for estradiol is described. Unlike heterogeneous immunoassays, which require time-consuming separation steps or expensive automated systems, homogeneous imm... |
|
Histochemical estrogen receptor assay.
Am. J. Clin. Pathol. 76(3) , 365, (1981)
|
|
Estrogen receptors in human breast cancer. II. Correlation between the histochemical method and biochemical assay.
Virchows Arch.,. B, Cell Pathol. 40(1) , 27-37, (1982) The present study defines criteria for determining the presence of estrogen-receptors in human breast carcinomas demonstrated by a histochemical assay using 17 beta-estradiol-carboxy-methyl-oxim-bovin... |
((((17β)-3,17-Dihydroxyestra-1,3,5(10)-trien-6-ylidene)amino)oxy)acetic acid |
Beta-Estradiol-6-one 6-(O-carboxymethyloxime) |
Acetic acid, 2-[[[(6E,17β)-3,17-dihydroxyestra-1(10),2,4-trien-6-ylidene]amino]oxy]- |
17β-estradiol 6-O-(carboxymethyl)oxime |
1,3,5[10]-ESTRATRIENE-3,17-DIOL-6-ONE 6-[O-CARBOXYMETHYL]OXIME |
17beta-estradiol 6-O-(carboxymethyl)oxime |
β-Estradiol-6-one 6-(O-carboxymethyloxime) |
SS-ESTRADIOL-6-ONE 6-(O-CARBOXYMETHYLOXIME) |
6-keto-1,3,5(10)estratriene-3,17β-diol 6-carboxymethyloxime |
({(E)-[(6E,17β)-3,17-Dihydroxyestra-1(10),2,4-trien-6-ylidene]amino}oxy)acetic acid |