951945-67-8

951945-67-8 structure
951945-67-8 structure
  • Name: viFSP1
  • Chemical Name: viFSP1
  • CAS Number: 951945-67-8
  • Molecular Formula: C16H17N3O3S
  • Molecular Weight: 331.39
  • Catalog: Signaling Pathways Apoptosis Ferroptosis
  • Create Date: 2024-01-30 03:47:11
  • Modify Date: 2024-01-30 03:47:11
  • viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. viFSP1 targets the highly conserved NAD(P)H binding pocket of FSP1 and directly inhibits FSP1. viFSP1 induces lipid peroxidation and has anticancer activity[1].

Name viFSP1
Description viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. viFSP1 targets the highly conserved NAD(P)H binding pocket of FSP1 and directly inhibits FSP1. viFSP1 induces lipid peroxidation and has anticancer activity[1].
Related Catalog
Target

FSP1[1]

References

[1]. Nakamura T et al. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815.  

Molecular Formula C16H17N3O3S
Molecular Weight 331.39