Vildagliptin-d7 structure
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Common Name | Vildagliptin-d7 | ||
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CAS Number | 1133208-42-0 | Molecular Weight | 310.44 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 531.3±50.0 °C at 760 mmHg | |
Molecular Formula | C17H18D7N3O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 275.1±30.1 °C |
Use of Vildagliptin-d7Vildagliptin-d7 is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1]. |
Name | Vildagliptin-d7 |
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Synonym | More Synonyms |
Description | Vildagliptin-d7 is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1]. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 531.3±50.0 °C at 760 mmHg |
Molecular Formula | C17H18D7N3O2 |
Molecular Weight | 310.44 |
Flash Point | 275.1±30.1 °C |
Exact Mass | 310.238617 |
LogP | -0.14 |
Vapour Pressure | 0.0±3.2 mmHg at 25°C |
Index of Refraction | 1.601 |
Vildagliptin-d7 |
2-Pyrrolidine-2,3,3,4,4,5,5-d7-carbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)- |
(2S)-1-{N-[(1r,3r)-3-Hydroxyadamantan-1-yl]glycyl}-2-(2H7)pyrrolidinecarbonitrile |