CaMKII-IN-1

Modify Date: 2024-01-07 21:44:47

CaMKII-IN-1 Structure
CaMKII-IN-1 structure
Common Name CaMKII-IN-1
CAS Number 1208123-85-6 Molecular Weight 548.09900
Density 1.4±0.1 g/cm3 Boiling Point 728.2±70.0 °C at 760 mmHg
Molecular Formula C29H30ClN5O2S Melting Point N/A
MSDS N/A Flash Point 394.2±35.7 °C

 Use of CaMKII-IN-1


CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.IC50 value: 63 nMTarget: CaMKII

 Names

Name N-{6-Benzyl-2-[(2-phenylethyl)amino]-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl}-3-chloro-2-methylbenzenesulfonamide
Synonym More Synonyms

 CaMKII-IN-1 Biological Activity

Description CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.IC50 value: 63 nMTarget: CaMKII
Related Catalog
References

[1]. Asano S, et al. 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6696-8.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 728.2±70.0 °C at 760 mmHg
Molecular Formula C29H30ClN5O2S
Molecular Weight 548.09900
Flash Point 394.2±35.7 °C
Exact Mass 547.18100
PSA 95.60000
LogP 5.48
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.670
Storage condition 2-8℃

 Synonyms

N-{6-Benzyl-2-[(2-phenylethyl)amino]-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl}-3-chloro-2-methylbenzenesulfonamide
Benzenesulfonamide, 3-chloro-2-methyl-N-[5,6,7,8-tetrahydro-2-[(2-phenylethyl)amino]-6-(phenylmethyl)pyrido[4,3-d]pyrimidin-4-yl]-
CaMKII-IN-1
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Price: $506/10mM*1mLinDMSO

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