M35

Modify Date: 2024-01-09 21:07:18

M35 structure	Common Name	M35
	CAS Number	142846-71-7	Molecular Weight	2233.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀₇H₁₅₃N₂₇O₂₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of M35

Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2].

Name	M35 Peptide
Synonym	More Synonyms

Description	Galanin Receptor Ligand M35 is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic islets. Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human GalR1 and GalR2, respectively[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
Target	Ki: 0.11 nM (GalR1), 2.0 nM (GalR2)[2]
References	[1]. Kask K, et al. Binding and agonist/antagonist actions of M35, galanin(1-13)-bradykinin(2-9)amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59(3):341-8. [2]. Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne). 2012 Dec 7;3:146.

Molecular Formula	C₁₀₇H₁₅₃N₂₇O₂₆
Molecular Weight	2233.60
Exact Mass	2232.15000
PSA	817.65000
LogP	2.16320

Safety Phrases	22-24/25

GWTLNSAGYLLGPPPGFSPFR-CONH2

L-Argininamide,glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl

M 35

Galanin-(1-13)-bradykinin-(2-9)-amide