DPP-4/GPR119 modulator 2

Modify Date: 2024-01-09 12:47:12

DPP-4/GPR119 modulator 2 Structure
DPP-4/GPR119 modulator 2 structure
Common Name DPP-4/GPR119 modulator 2
CAS Number 2010927-65-6 Molecular Weight 560.69
Density N/A Boiling Point N/A
Molecular Formula C30H40N8O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DPP-4/GPR119 modulator 2


DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 µM for DPP-IV and an EC50 of 0.95 µM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research[1].

 Names

Name DPP-4/GPR119 modulator 2

 DPP-4/GPR119 modulator 2 Biological Activity

Description DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 µM for DPP-IV and an EC50 of 0.95 µM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research[1].
Related Catalog
Target

IC50: 0.22 µM (DPP-IV)[1]. EC50: 0.95 µM (GPR119)[1]

References

[1]. Li G, et al. The optimization of xanthine derivatives leading to HBK001 hydrochloride as a potent dual ligand targeting DPP-IV and GPR119. Eur J Med Chem. 2020 Feb 15;188:112017.

 Chemical & Physical Properties

Molecular Formula C30H40N8O3
Molecular Weight 560.69