PROTAC K-Ras Degrader-1

Modify Date: 2024-01-11 14:09:52

PROTAC K-Ras Degrader-1 Structure
PROTAC K-Ras Degrader-1 structure
Common Name PROTAC K-Ras Degrader-1
CAS Number 2378258-52-5 Molecular Weight 999.12
Density N/A Boiling Point N/A
Molecular Formula C53H62N10O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC K-Ras Degrader-1


PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].

 Names

Name PROTAC K-Ras Degrader-1

 PROTAC K-Ras Degrader-1 Biological Activity

Description PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].
Related Catalog
Target

KRAS(G12C)

Cereblon

References

[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.

 Chemical & Physical Properties

Molecular Formula C53H62N10O10
Molecular Weight 999.12
Storage condition -20°C