GSK345931A

Modify Date: 2024-01-03 20:22:49

GSK345931A Structure
GSK345931A structure
Common Name GSK345931A
CAS Number 869499-38-7 Molecular Weight 403.83
Density N/A Boiling Point N/A
Molecular Formula C22H19ClNNaO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK345931A


GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].

 Names

Name sodium,6-[2-[5-chloro-2-(2-methylpropoxy)phenyl]phenyl]pyridine-2-carboxylate
Synonym More Synonyms

 GSK345931A Biological Activity

Description GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain[1].
Related Catalog
Target

EP1

References

[1]. Hall A, et al. Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain. Bioorg Med Chem Lett. 2009 Jan 15;19(2):497-501.  

 Chemical & Physical Properties

Molecular Formula C22H19ClNNaO3
Molecular Weight 403.83
Exact Mass 403.09500
PSA 62.25000
LogP 4.46730

 Synonyms

unii-u73bv4mml7
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