甘露醇二磺酸酯

甘露醇二磺酸酯名称

[ CAS 号 ]:
1187-00-4

[ 中文名 ]:
甘露醇二磺酸酯

[ 英文名 ]:
D-Mannitol,1,6-dimethanesulfonate

[英文别名 ]:

O1,O6-Dimethansulfonyl-D-mannit
Mannogranol
D-Mannitol busulphan
D-Mannitol busulfan
O1,O6-bis-methanesulfonyl-D-mannitol
1,6-Bis-methansulfonyl-D-mannit
MANNITOL,1,6-DIMETHYLSULPHONATE,D
1,6-Di-O-methansulfonyl-D-mannitol
2511 C. B.
O1,O6-Bis-methansulfonyl-D-mannit

甘露醇二磺酸酯物理化学性质

[ 密度 ]:
1.635g/cm3

[ 沸点 ]:
721.3ºC at 760 mmHg

[ 熔点 ]:
134-136 °C

[ 分子式 ]:
C₈H₁₈O₁₀S₂

[ 分子量 ]:
338.35300

[ 闪点 ]:
390ºC

[ 精确质量 ]:
338.03400

[ PSA ]:
184.42000

[ 蒸汽压 ]:
5.01E-24mmHg at 25°C

[ 折射率 ]:
1.553

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

甘露醇二磺酸酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OP2975000

CHEMICAL NAME :: Mannitol, 1,6-dimethanesulfonate, D-

CAS REGISTRY NUMBER :: 1187-00-4

LAST UPDATED :: 199707

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C8-H18-O10-S2

MOLECULAR WEIGHT :: 338.38

WISWESSER LINE NOTATION :: WS1&O1YQYQYQYQ1OSW1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Blood - normocytic anemia Blood - thrombocytopenia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - agranulocytosis Blood - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - agranulocytosis Blood - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 mg/kg/4W

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rabbit Bone marrow

DOSE/DURATION :: 1700 umol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1705,1976

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甘露醇二磺酸酯安全信息

[ 海关编码 ]:
2905499000

甘露醇二磺酸酯海关

[ 海关编码 ]: 2905499000

[ 中文概述 ]:
2905499000 其他多元醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2905499000 other polyhydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%