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替可克肽

替可克肽用途

Tetracosactide (INN) 是肾上腺皮质激素 (ACTH) 的类似物,有刺激肾上腺皮质激素分泌的生物活性。
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替可克肽名称

[ CAS 号 ]:
16960-16-0

[ 中文名 ]:
替可克肽

[ 英文名 ]:
Adrenocorticotropic Hormone Fragment 1-24 human

[中文别名 ]:

[英文别名 ]:

替可克肽生物活性

替可克肽物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 分子式 ]:
C136H210N40O31S

[ 分子量 ]:
2933.437

[ 精确质量 ]:
2931.580566

[ PSA ]:
1184.02000

[ LogP ]:
-3.27

[ 折射率 ]:
1.681

[ 储存条件 ]:
−20°C

替可克肽毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GM7915000
CHEMICAL NAME :
alpha(sup 1-24)-Corticotropin
CAS REGISTRY NUMBER :
16960-16-0
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C136-H210-N40-O31-S
MOLECULAR WEIGHT :
2933.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
5 ug/kg
TOXIC EFFECTS :
Cardiac - change in rate Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes
REFERENCE :
JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 237,879,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4549 No. of Facilities: 24 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1071 (estimated) No. of Female Employees: 546 (estimated)
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替可克肽安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
GM7915000

替可克肽文献

An LC-MS/MS method for steroid profiling during adrenal venous sampling for investigation of primary aldosteronism.

J. Steroid Biochem. Mol. Biol. 145 , 75-84, (2015)

Steroid profiling for diagnosis of endocrine disorders featuring disordered production of steroid hormones is now possible from advances in liquid chromatography with tandem mass spectrometry (LC-MS/M...

The relationship between vitamin D status and adrenal insufficiency in critically ill children.

J. Clin. Endocrinol. Metab. 98(5) , E877-81, (2013)

Recent studies in critically ill populations have suggested both adrenal insufficiency (AI) and vitamin D deficiency to be associated with worse clinical outcome. There are multiple mechanisms through...

Free and total plasma cortisol measured by immunoassay and mass spectrometry following ACTH₁₋₂₄ stimulation in the assessment of pituitary patients.

J. Clin. Endocrinol. Metab. 98(5) , 1883-90, (2013)

Measurement of plasma cortisol by immunoassay after ACTH₁₋₂₄ stimulation is used to assess the hypothalamic-pituitary-adrenal (HPA) axis. Liquid chromatography-tandem mass spectrometry (LCMS) has grea...


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推荐生产厂家/供应商:

公司名:吉尔生化(上海)有限公司

区域:上海市闵行区

价格:
$需询单/1kg

联系人:杨经理

产品详情:Tetracosactide Acetate


公司名:上海脉铂医药科技有限公司

区域:上海市嘉定区

价格:
¥2463.33/5mg

联系人:李先生

产品详情:替可克肽;二十四肽促皮质素;合成促皮质素


公司名:上海阿拉丁生化科技股份有限公司

区域:上海市浦东新区

价格:
¥630.9/1mg ¥2969.9/25mg ¥969.9/5mg ¥需询单/1g

联系人:阿拉丁李高志

产品详情:Adrenocorticotropic Hormone Fragment 1-24 human


公司名:上海创赛科技有限公司

区域:上海市嘉定区

价格:
¥需询单/1g ¥644.0/1mg ¥989.0/5mg ¥2969.0/25mg

联系人:夏言

产品详情:[Perfemiker]促肾上腺皮质激素片段 (1-24),人,≥97% (HPLC)


公司名:福州飞净生物科技有限公司

区域:福州市闽侯县

价格:
¥490.0/10mg ¥1120.0/50mg ¥1610.0/100mg ¥需询单/1g

联系人:小飞

产品详情:促肾上腺皮质激素 ACTH(1-24), human


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