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透明质酸酶

透明质酸酶用途

Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) 是一种天然存在的酶,通过糖苷键的分裂使透明质酸解聚,并用于局部麻醉剂添加剂。

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透明质酸酶名称

[ CAS 号 ]:
37326-33-3

[ 中文名 ]:
透明质酸酶I-S

[ 英文名 ]:
Hyaluronidase

[中文别名 ]:

透明质酸酶

[英文别名 ]:

2,4-Bis(1,3-benzodioxol-5-yl)-4-oxobutanoic acid
Neopermease
Hydase
EINECS 253-464-3
Hyaluronoglucosidase
MFCD00131351
Hyaluronoglucosaminidase
Chondroitinase

透明质酸酶生物活性

[ 描述 ]:

Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) 是一种天然存在的酶,通过糖苷键的分裂使透明质酸解聚,并用于局部麻醉剂添加剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7.

[2]. Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.

透明质酸酶物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
598.6±50.0 °C at 760 mmHg

[ 分子式 ]:
C₁₈H₁₄O₇

[ 分子量 ]:
342.300

[ 闪点 ]:
223.2±23.6 °C

[ 精确质量 ]:
342.073944

[ LogP ]:
2.41

[ 外观性状 ]:
powder | yellow-brown

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.642

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
Soluble in water, practically insoluble in acetone and in anhydrous ethanol

透明质酸酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

透明质酸酶文献

Faster fertilization rate in conspecific versus heterospecific matings in house mice.

Evolution 63 , 20-8, (2010)

Barriers to gene flow can arise at any stage in the reproductive sequence. Most studies of reproductive isolation focus on premating or postzygotic phenotypes, leaving the importance of differences in...

Putting on the brakes: Bacterial impediment of wound healing.

Sci. Rep. 5 , 14003, (2015)

The epithelium provides a crucial barrier to infection, and its integrity requires efficient wound healing. Bacterial cells and secretomes from a subset of tested species of bacteria inhibited human a...

Focal experimental injury leads to widespread gene expression and histologic changes in equine flexor tendons.

PLoS ONE 10(4) , e0122220, (2015)

It is not known how extensively a localised flexor tendon injury affects the entire tendon. This study examined the extent of and relationship between histopathologic and gene expression changes in eq...

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