黄曲霉毒素G2

黄曲霉毒素G2用途

Aflatoxin G2 是一种主要的天然存在的黄曲霉毒素。Aflatoxin G2 是由 Aspergillus flavus 和 Aspergillus parasiticus 产生的一种霉菌毒素。毒性顺序为 Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2。

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黄曲霉毒素G2名称

[ CAS 号 ]:
7241-98-7

[ 中文名 ]:
黄曲霉素G2

[ 英文名 ]:
aflatoxin g2

[中文别名 ]:

[英文别名 ]:

AflatoxinG2,crystalline
EINECS 230-643-4
9,10,10aalpha-hexahydro-5-methoxy-lph
AF G2
Dihydroaflatoxin G1
Aflatoxin G(2)
MFCD00078141
10a-hexahydro-5-methoxy-1(7ar-cis)

黄曲霉毒素G2生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kumar P, et al. Aflatoxins: A Global Concern for Food Safety, Human Health and Their Management. Front Microbiol. 2017 Jan 17;7:2170.

黄曲霉毒素G2物理化学性质

[ 密度 ]:
1.55 g/cm3

[ 沸点 ]:
602.5ºC at 760 mmHg

[ 熔点 ]:
237-240ºC

[ 分子式 ]:
C₁₇H₁₄O₇

[ 分子量 ]:
330.28900

[ 闪点 ]:
269.6ºC

[ 精确质量 ]:
330.07400

[ PSA ]:
84.20000

[ LogP ]:
1.73690

[ 折射率 ]:
1.654

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

黄曲霉毒素G2MSDS

黄曲霉毒素G2毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LV1700000

CAS REGISTRY NUMBER :: 7241-98-7

LAST UPDATED :: 199510

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C17-H14-O7

MOLECULAR WEIGHT :: 330.31

WISWESSER LINE NOTATION :: T F6 C6 B655 DOV GVO PO ROT&&TTJ MO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 2450 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - duck

DOSE/DURATION :: 1420 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 3300 ug/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 1,759,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 1,145,1972 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 56,245,1993 TOXICOLOGY REVIEW BAREA8 Bacteriological Reviews. (Washington, DC) V.1-41, 1937-77. Volume(issue)/page/year: 30,460,1966 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974 TOXICOLOGY REVIEW IJNDAN Indian Journal of Nutrition and Dietetics. (Sri Avinashilingam Home Science College for Women, Coimbatore 641 043, India) V.7- 1970- Volume(issue)/page/year: 8,85,1971

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黄曲霉毒素G2安全信息

[ 符号 ]:

GHS02, GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H304-H315-H319-H340-H350-H372

[ 警示性声明 ]:
P201-P210-P301 + P310-P305 + P351 + P338-P308 + P313-P331

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T+: Very toxic;

[ 风险声明 (欧洲) ]:
R45

[ 安全声明 (欧洲) ]:
S28;S45;S53;S36/S37

[ 危险品运输编码 ]:
UN 3462 6

[ WGK德国 ]:
3

[ RTECS号 ]:
LV1700000

[ 包装等级 ]:
I

[ 危险类别 ]:
6.1(a)

[ 海关编码 ]:
30029090

黄曲霉毒素G2合成路线

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黄曲霉毒素G2文献

Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers.

Food Chem. Toxicol. 74 , 120-30, (2014)

The T-2 and HT-2 toxins, the main metabolites of Fusarium poae, induce toxicity in broilers and accumulate in tissues. Consequently, during the breeding process of broilers, diets are frequently suppl...

Development and validation of an UHPLC-MS/MS method for the determination of mycotoxins in grass silages.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 2101-12, (2015)

An ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) multi-mycotoxin analytical method was developed to simultaneously identify and quantify 20 mycotoxins in grass si...

A multi-analyte LC-MS/MS method for the analysis of 23 mycotoxins in different sorghum varieties: the forgotten sample matrix.

Food Chem. 177 , 397-404, (2015)

An LC-MS/MS method was developed and validated for the detection and quantification of 23 mycotoxins in different varieties of sorghum. The method performance characteristics were as follows: suitable...

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