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谷氨酸脱氢酶

谷氨酸脱氢酶用途

谷氨酸脱氢酶NAD(P)(GLDH)可在肝细胞、肾组织、脑、肌肉和肠细胞中发现。谷氨酸脱氢酶NAD(P)经常用于生化研究。谷氨酸脱氢酶是一种线粒体酶,作为尿素循环的一部分,它催化谷氨酸可逆氧化脱氨为α-酮戊二酸(α-KG)[1]。

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谷氨酸脱氢酶名称

[ CAS 号 ]:
9029-12-3

[ 中文名 ]:
L-谷氨酸脱氢酶悬浮液(牛肝)

[ 英文名 ]:
gldh

[英文别名 ]:

MFCD00131461

谷氨酸脱氢酶生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Smith HQ, et al. Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point. Neurochem Res. 2019 Jan;44(1):117-132.

谷氨酸脱氢酶物理化学性质

[ 外观性状 ]:
solution (viscous) | amber

[ 储存条件 ]:
2-8°C

谷氨酸脱氢酶安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

谷氨酸脱氢酶文献

High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.

PLoS ONE 10 , e0127785, (2015)

The cystine-glutamate antiporter (system xc-) is a Na+-independent amino acid transporter that exchanges extracellular cystine for intracellular glutamate. It is thought to play a critical role in cel...

Extensive Charge Reduction and Dissociation of Intact Protein Complexes Following Electron Transfer on a Quadrupole-Ion Mobility-Time-of-Flight MS.

J. Am. Soc. Mass Spectrom. 26 , 1068-76, (2015)

Non-dissociative charge reduction, typically considered to be an unwanted side reaction in electron transfer dissociation (ETD) experiments, can be enhanced significantly in order to reduce the charge...

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

Nature 496(7443) , 101-5, (2013)

Cancer cells have metabolic dependencies that distinguish them from their normal counterparts. Among these dependencies is an increased use of the amino acid glutamine to fuel anabolic processes. Inde...

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