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谷胱甘肽乙基酯

谷胱甘肽乙基酯用途

Glutathione ethyl ester 是细胞渗透性谷胱甘肽 GSH 供体,为卵母细胞提供高效的谷胱甘肽供应。Glutathione ethyl ester 通过增强抗氧化防御作用对胚胎体外生产有积极作用。

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谷胱甘肽乙基酯名称

[ CAS 号 ]:
92614-59-0

[ 中文名 ]:
谷胱甘肽乙基酯

[ 英文名 ]:
Glutathione-monoethyl ester (reduced)

[英文别名 ]:

GSH-MEE
Glutathione monoethyl ester
Glutathione reduced ethyl ester
GSH monoethylester
Ethyl L-γ-glutamyl-L-cysteinylglycinate
Glycine, L-γ-glutamyl-L-cysteinyl-, ethyl ester
|A-Glu-Cys-Gly-OEt

谷胱甘肽乙基酯生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 炎症/免疫

[ 靶点 ]

IC50：GSH[1]

[参考文献]

[1]. F Magata, et al. Glutathione ethyl ester improved the age-induced decline in the developmental competence of bovine oocytes. Theriogenology. 2021 Jun:167:37-43.

谷胱甘肽乙基酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
644.3±55.0 °C at 760 mmHg

[ 分子式 ]:
C₁₂H₂₁N₃O₆S

[ 分子量 ]:
335.38

[ 闪点 ]:
343.5±31.5 °C

[ 精确质量 ]:
335.115112

[ PSA ]:
186.62000

[ LogP ]:
0.00

[ 蒸汽压 ]:
0.0±4.1 mmHg at 25°C

[ 折射率 ]:
1.536

谷胱甘肽乙基酯MSDS

详细MSDS(安全技术说明书)

谷胱甘肽乙基酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

谷胱甘肽乙基酯文献

PRIMA-1Met induces myeloma cell death independent of p53 by impairing the GSH/ROS balance.

Blood 124(10) , 1626-36, (2014)

The aim of this study was to assess the efficiency of p53 reactivation and induction of massive apoptosis (PRIMA-1(Met)) in inducing myeloma cell death, using 27 human myeloma cell lines (HMCLs) and 2...

Dual-targeting of aberrant glucose metabolism in glioblastoma.

J. Exp. Clin. Cancer Res 34 , 14, (2015)

Glioblastoma (GBM) is the most common and malignant primary brain tumor. In contrast to some other tumor types, aberrant glucose metabolism is an important component of GBM growth and chemoresistance....

Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes.

Am. J. Physiol. Lung Cell. Mol. Physiol. 307(5) , L364-73, (2014)

This study assessed the effect of extended exposure to cigarette smoke extract (CSE) on tissue repair functions in lung fibroblasts. Human fetal (HFL-1) and adult lung fibroblasts were exposed to CSE ...

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