Synthesis

Synthesis of primary thioamides from nitriles and hydrogen sulfide catalyzed by anion-exchange resin

R Liboska, D Zyka, M Bobek

文献索引：Liboska, Radek; Zyka, Daniel; Bobek, Miroslav Synthesis, 2002 , # 12 p. 1649 - 1651

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被引用次数: 18

摘要

Abstract A new method has been developed for converting nitriles into primary thioamides. Treatment of various nitriles (Table [1], entries 1-12) with gaseous hydrogen sulfide in a mixture of methanol-water or ethanol-water and in the presence of anion-exchange resin (Dowex 1X8, SH-form) at room temperature and ambient pressure gave the corresponding thioamides in 25-96% yield.