(4) RK Robins and HH Lin, TIXIS JOURNAL, 79, 490 (1957). fore seemed desirable to prepare G-chloro-7-methylpurine (VI) as a candidate anti-tumor agent. Since preliminary methylation studies of 6-chloropurine gave a difficultly separable mixture of the 7-methyl and 9-methyl isomers, the possible preparation of 6-chloro-7-methylpurine (VI) from 7- methylhypoxanthine (V) was investigated. Earlier methods of preparation of 7- ...
