A structure–activity study of spermicidal and anti-HIV properties of hydroxylated cationic surfactants

…, CL Curfman, GF Doncel, TC Dudding, PS Savle…

文献索引：Wong, Yue-Ling; Hubieki; Curfman, Christopher L; Doncel, Gustavo F; Dudding, Travis C; Savle, Prashant S; Gandour, Richard D Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 11 p. 3599 - 3608

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被引用次数: 31

摘要

The syntheses of 2-hydroxy-N-(2-hydroxyethyl)-N, N-dimethylhexadecan-1-aminium chloride [1 (16) Cl] and iodide [1 (16) I], 2-hydroxy-N, N, N-trimethylhexadecan-1-aminium chloride (6), N-(2-hydroxyethyl)-N, N-dimethylhexadecan-1-aminium chloride (8), N, N-bis (2- hydroxyethyl)-N-methylhexadecan-1-aminium chloride (11), and 2-hydroxy-N-(2- hydroxyethyl)-N, N-dimethyl-4-oxahexadecan-1-aminium chloride (14) are reported along ...