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Facile synthesis of isoxazole 4-and 5-carbaldehydes and their conversion to isoxazolyl-1, 4-dihydropyridines

…, S Bavili-Tabrizi, M Hashemi-Gohare…

文献索引:Mirzaei; Bavili-Tabrizi; Hashemi-Gohare; Zare-Neirizi; Edjlali Organic Preparations and Procedures International, 2003 , vol. 35, # 2 p. 207 - 214

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被引用次数: 7

摘要

Isoxazoles' are important building blocks in the construction of more complex systems including a variety of natural products? Isoxazole carbaldehydes are starting materials for isoxazole-1, 4-dihydropyridine~.~ However, the instability of isoxazoles in the presence of oxidizing agents in acidic media (ring opening, Id and in some cases ring oxidationle) narrows the choice of reagents for the oxidation of isoxazolyl carbinols to the ...