HE success of isoniazid in the treatment of tuberculosis has led to T the preparation and testing for antituberculosis activity of many other acid hydrazides and related compounds (Steenken & Wolinsky, 1952; Bernstein, Jambor, Lott, Pansy, Steinberg & Yale, 1953; Bavin, James, Kay, Lazare & Seymour, 1955). In the aliphatic series the most effective acid hydrazide tested was cyanacethydrazide (Hartyl, 1954), which was claimed to be ...
