Novel KCNQ2/Q3 agonists as potential therapeutics for epilepsy and neuropathic pain

PC Fritch, G McNaughton-Smith…

文献索引：Chaudhuri, Narayan C. Synthetic Communications, 1996 , vol. 26, # 20 p. 3783 - 3790

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被引用次数: 33

摘要

... Volume: Page: ... C, 6 h, 74% or 1.0 M isopropyl chloroformate solution in toluene, NMM, THF, 23 °C, 6 h, 64% or Boc 2 O, THF, 23 °C, 3 h ... compd, Y, R, KCNQ2/Q3 (efflux) EC 50 (μM) a, mouse MES PO 20 mg/kg, mouse MES PO 10 mg/kg, mouse MES PO EC 50 (mg ...