Alkylations of Phenylacetic Esters with Halides by Means of Sodium Amide in Liquid Ammonia. Comparisons with Alkylations of Phenylacetic Acid1a

WG Kenyon, RB Meyer, CR Hauser

文献索引：Kenyon,W.G. et al. Journal of Organic Chemistry, 1963 , vol. 28, p. 3108 - 3112

全文：HTML全文

被引用次数: 15

摘要

Ethyl phenylacetate was alkylated with alkyl and aralkyl halides through the sodio ester, which was prepared by means of sodium amide in liquid ammonia. The methyl, n-butyl, benzyl, and the a-and p-phenylethyl derivatives uere obtained in high yields but the a $- diphenylethyl derivative wes produced in only fair yield along with stilbene. Similarly, t-butyl phenylacetate was alkylated with representative halidee through the sodio ester. The a- ...