An efficient and enantioselective hydrogenation of N-acetylamino phenyl acrylic acids was successfully developed by using ruthenium catalyst. This methodology is important in the field of pharmaceuticals and provides a new process for the preparation of unnatural amino acids and tamsulosin chiral intermediate. ... [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource: Full ...
[Liu, Si-Jie; Yang, Liu; Liu, Xiao-Guang; Luo, Ying; Cao, Zi-Jian; Wan, David Chi Cheong; Lin, Huang-Quan; Hu, Chun Letters in Drug Design and Discovery, 2010 , vol. 7, # 1 p. 5 - 8]
