Novel Building Blocks: 1??Aryl??2??chloro??1??ethoxyethenes–Preparations and Transformations

M Yoshimatsu, M Sakai…

文献索引：Yoshimatsu, Mitsuhiro; Sakai, Miho; Moriura, Eri European Journal of Organic Chemistry, 2007 , # 3 p. 498 - 507

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被引用次数: 2

摘要

Abstract We described here a simple method for the preparation of 1-aryl-2-chloro-1- ethoxyethenes 2a–u, which are prodrugs for Alzheimer's disease, by the reaction of dichloroacetaldehyde diethyl acetal with various aryl and alkenyllithium compounds in high yields.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)