Tetrahedron: Asymmetry

Resolution of N-protected amino acid esters using whole cells of Candida parapsilosis ATCC 7330

S Stella, A Chadha

文献索引：Stella, Selvaraj; Chadha, Anju Tetrahedron Asymmetry, 2010 , vol. 21, # 4 p. 457 - 460

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被引用次数: 18

摘要

Whole cells of Candida parapsilosis ATCC 7330 were used for the resolution of N-acetyl amino acid esters. Excellent enantioselectivities (E= 40 to> 500) were achieved for the resolution of N-protected protein and non-protein amino acid esters giving good yields (28– 50%) and high enantiomeric excesses (up to> 99%) for both enantiomers.