Development of a Practical Synthesis of a Functionalized Pyrrolo [2, 1-f][1, 2, 4] triazine Nucleus

B Zheng, DA Conlon, RM Corbett, M Chau…

文献索引：Organic Process Research and Development, , vol. 16, # 11 p. 1846 - 1853

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被引用次数: 8

摘要

... Organic Process Research & Development. ... Among the solvents investigated, toluene provided the best in-process impurity profile of keto ester 21.(12). figure ... Upon performing the alkylation procedure on a slightly larger scale (10 g), it was found that the yield was not ...