A new route to 2??amino??or 2??hydroxy??3??pyridinecarboxylic acid derivatives

K Ito, S Yokokura, S Miyajima

文献索引：Ito, Kunio; Yokokura, Seiichi; Miyajima, Shingo Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 773 - 778

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被引用次数: 8

摘要

Abstract Schiff's bases derived from ketones and t-butylamine (1) reacted with methyl methoxymethylenemalonate to give 2-hydroxy-3-pyridinecarboxylates. Similarly, treatment of 1 with ethoxymethylenemalononitrile gave 2-amino-3-pyridinecarbonitriles. Compounds 1 on reaction with ethyl 2-cyano-3-ethoxypropenoate afforded 2-amino-3- pyridinecarboxylates.