Synlett

Microwave-Assisted Preparation of Quinolone and Quinoline Derivatives

M Albrecht, O Osetska, T Rantanen, R Fröhlich…

文献索引：Albrecht, Markus; Osetska, Olga; Rantanen, Toni; Froehlich, Roland; Bolm, Carsten Synlett, 2010 , # 7 p. 1081 - 1084

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被引用次数: 2

摘要

Abstract Quinolinone derivatives can be obtained in microwave-assisted syntheses by reaction of aniline derivatives with acetylene dicarboxylic esters, a malonic acid diester or β- keto ester derivatives. The reaction proceeds under mild conditions in short reaction times. Two of the quinolinones were transformed into the corresponding 4-chloroquinolines either by conventional heating or in a microwave-assisted reaction. Further modifications ...