Organic process research & development

Reductions of aromatic amino acids and derivatives

DJ Ager, I Prakash

文献索引：Ager, David J.; Prakash, Indra Organic Process Research and Development, 2003 , vol. 7, # 2 p. 164 - 167

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被引用次数: 6

摘要

Previous reported methods for the synthesis of l-cyclohexylalanine (1) involve the reduction of l-phenylalanine (4) using platinum oxide or platinum on carbon in acetic acid. 3 Rhodium in the presence of acid has been used for the reduction of phenylglycine (vide infra). 4 Synthesis of l-cyclohexylalanine amide (3) is reported in a patent without any experimental detail. 2 l-Cyclohexylalaninol (2) 5 was prepared by the sodium or calcium borohydride reduction of the l-Boc- ...