Lipase-mediated desymmetrization of glycerol with aromatic and aliphatic anhydrides

DI Batovska, S Tsubota, Y Kato, Y Asano…

文献索引：Batovska, Daniela I.; Tsubota, Shuichirou; Kato, Yasuo; Asano, Yasuhisa; Ubukata, Makoto Tetrahedron Asymmetry, 2004 , vol. 15, # 22 p. 3551 - 3559

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被引用次数: 27

摘要

Chirazyme L-2 (Candida antarctica) catalyzed esterification of glycerol with aromatic and aliphatic anhydrides in 1, 4-dioxane is described. All the aromatic monoacylglycerols (MAGs) were produced as (R)-enantiomers, while aliphatic MAGs were obtained either as racemic mixtures or the (S)-enantiomers. The influence of substituted aromatic rings, chain length, and presence of a conjugated double bond in the acyl donor moiety on the ...