Enantioselective Homogeneous Hydrogenation of Monosubstituted Pyridines and Furans

M Studer, C Wedemeyer-Exl, F Spindler…

文献索引：Studer, Martin; Wedemeyer-Exl, Christina; Spindler, Felix; Blaser, Hans-Ulrich Monatshefte fur Chemie, 2000 , vol. 131, # 12 p. 1335 - 1343

全文：HTML全文

被引用次数: 77

摘要

Summary. The first case of an enantioselective hydrogenation of monosubstituted pyridines and furans with homogeneous rhodium diphosphine catalysts with low but significant enantioselectivities and catalyst activities is reported. Best enantioselectivities (ee s of 24– 27%) were obtained for the hydrogenation of 2-and 3-pyridine carboxylic acid ethyl ester and 2-furan carboxylic acid with catalysts prepared in situ from [Rh (nbd) 2] BF 4 and the ...

~64%

~33%

~99%

~96%

~99%

~99%

Electrolytic synthesis of nipecotic acid ethyl ester

[Muldakhmetov; Gazaliev; Kirilyus; Fazylov Russian Journal of Applied Chemistry, 2007 , vol. 80, # 7 p. 1087 - 1089]

Continuous flow hydrogenation of functionalized pyridines

[Irfan, Muhammed; Petricci, Elena; Glasnov, Toma N.; Taddei, Maurizio; Kappe, C. Oliver European Journal of Organic Chemistry, 2009 , # 9 p. 1327 - 1334]

The Catalytic Hydrogenation of Esters to Alcohols. II

[Folkers; Adkins Journal of the American Chemical Society, 1932 , vol. 54, p. 1146]

SYNTHESIS OF A NEW BICYCLIC NITROGEN RING. ISOGRANATANINE DE...

[McElvain; Adams Journal of the American Chemical Society, 1923 , vol. 45, p. 2740,2747]