One-Carbon Homologation of Carboxylic Acids via BtCH2TMS: A Safe Alternative to the Arndt-Eistert Reaction

…, S Zhang, AHM Hussein, Y Fang, PJ Steel

文献索引：Katritzky; Zhang; Haleem; Hussein; Fang; Steel Journal of Organic Chemistry, 2001 , vol. 66, # 16 p. 5606 - 5612

被引用次数: 27

摘要

Carboxylic acids are converted into the corresponding homologated acids or esters, using easily available 1-(trimethylsilylmethyl) benzotriazole (1) as a one-carbon synthon. The effectiveness of the reaction has been investigated on six aryl and seven alkyl carboxylic acids.

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