Chemical Communications

Alcohol assisted C–C bond breaking: copper-catalyzed deacetylative α-arylation of β-keto esters and amides

J Ke, C He, H Liu, H Xu, A Lei

文献索引：Ke, Jie; He, Chuan; Liu, Huiying; Xu, Huan; Lei, Aiwen Chemical Communications, 2013 , vol. 49, # 60 p. 6767 - 6769

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被引用次数: 4

摘要

A method of alcohol-assisted copper-catalyzed highly selective deacetylative α-arylation of β- keto esters and amides has been demonstrated, which illustrated an efficient example of achieving α-aryl esters and amides. From the synthetic point of view, this arylation protocol is general and practical, representing a simple way to produce α-arylated carbonyl compounds from basic starting materials at low cost.