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Development of a practical and reliable synthesis of laquinimod

J Wennerberg, A Björk, T Fristedt…

文献索引:Organic Process Research and Development, , vol. 11, # 4 p. 674 - 680

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被引用次数: 16

摘要

... Organic Process Research & Development. ... in the two-step procedure is more than 10% higher (82%) than the yield in the corresponding one-pot procedure (71 ... 2b,6 Toluene and the formed alcohol are distilled off during the process, and the distillation rate greatly influences the ...