Structural confirmation of the dihydrosphinganine and fatty acid constituents of the dental pathogen Porphyromonas gingivalis

…, A Onorato, FC Nichols, MD Morton, AI Saleh…

文献索引：Mun, JiYoung; Onorato, Amber; Nichols, Frank C.; Morton, Martha D.; Saleh, Abdullah I.; Welzel, Morgan; Smith, Michael B. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 23 p. 3826 - 3833

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被引用次数: 15

摘要

Porphyromonas gingivalis, a recognized periodontal pathogen, is a source of sphinganine bases, fatty acids, free ceramides as well as complex lipids that potentiate interleukin-1b- mediated secretory responses in gingival fibroblasts. The purpose of this study is the structural verification of the sphinganine bases and fatty acids that had been proposed as major components of the complex lipids found in P. gingivalis. The putative C17, C18, and ...