New labile metabolites derived from tryptophan and bearing oxygen functions in positions 5 and 7 have been prepared and correlated with regard to their actual and potential significance in various biological systems (Table I). By modifications of the Nenitzescu-van der Lee synthesis 5-and 7-hydroxytryptophan,-tryptamine and-(hetero) auxin have been prepared in good yield. The availability of these synthetic substances made possible ...
