The Synthesis of Substituted Benzo [c] chromen??6??ones by a Suzuki Coupling and Lactonization Sequence Using Ionic Liquids–from Laboratory Scale to Multi?? …

…, J Bergwerff, R Van der Eem, J Basten

文献索引：Kemperman, Gerardus J.; Ter Horst; Van De Goor; Roeters; Bergwerff; Van Der Eem; Basten European Journal of Organic Chemistry, 2006 , # 14 p. 3169 - 3174

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被引用次数: 28

摘要

Abstract A series of benzo [c] chromen-6-ones are prepared by a Suzuki coupling and lactonization sequence starting with 2-methoxyphenylboronic acids and methyl 2- bromobenzoate derivatives. The use of ionic liquids in this synthesis has been explored. It was found that the Suzuki coupling proceeds much faster when a catalytic amount of the ionic liquid [BMIM][PF 6] is used. By using the Lewis acidic ionic liquids [BMIM][Al 2 Cl 7] ...