Isocoumarine derivatives are an important class of natural lactones possessing many kinds of biological activity [1]. A whole number of synthetic isocoumarines are of great interest as pharmaceuticals with antifungal [2], antibacterial [2b], anticoagulant activity [3], human leukocyte elastase inhibitors [4]. The highly reactive heterocyclic ring of isocoumarine makes it an attractive synthon for the synthesis of other types of hetero-and carbocyclic ...