Chemistry Letters

Chemoselective Reduction of. ALPHA.-Imino Carbonyl Compounds into. ALPHA.-Amino Carbonyl Compounds with Titanium Tetraiodide.

M Shimizu, T Sahara, R Hayakawa

文献索引：Shimizu, Makoto; Sahara, Tetsuya; Hayakawa, Ryuuichirou Chemistry Letters, 2001 , # 8 p. 792 - 793

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被引用次数: 11

摘要

In connection with exploration into new biologically active compounds, it is highly desirable to develop ready methods for the preparation of α-amino carbonyl compounds, since many of targeted molecules in such field possess amino carbonyl and/or amino alcohol moieties.1,2 For the introduction of amino groups, reduction of imines is one of the most accessible methodologies,3 which involve metal borohydride reductions and hydrogenation in the presence of transition metal ...