Probing the importance of spacial and conformational domains in captopril analogs for angiotensin converting enzyme activity

S Hanessian, U Reinhold, M Saulnier…

文献索引：Hanessian, Stephen; Reinhold, Ulrich; Saulnier, Michel; Claridge, Stephen Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 16 p. 2123 - 2128

全文：HTML全文

被引用次数: 44

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A new synthesis of 4,5-methano-L-prolines and the enzymatic activity of the corresponding N-(3-mercapto-2-R-methyl-propionyl) analogs as inhibitors of angiotensin converting enzyme are described. ... For excellent summaries, see Burger's Medicinal Chemistry and Drug ...