Synthesis and biological evaluation of isosteric analogs of mandipropamid for the control of Oomycete pathogens

…, ZJ Wang, LZ Wang, X Zhang, WL Dong…

文献索引：Su, Na; Wang, Zhen-Jun; Wang, Li-Zhong; Zhang, Xiao; Dong, Wei-Li; Wang, Hong-Xue; Li, Zheng-Ming; Zhao, Wei-Guang Chemical Biology and Drug Design, 2011 , vol. 78, # 1 p. 101 - 111

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被引用次数: 8

摘要

A series of isosteric analogs of mandipropamid were designed and synthesized via'click chemistry'. The amide bond of mandipropamid was substituted by a 1, 2, 3-triazole functional group. The bioassay results have indicated that some of the title compounds exhibited moderate fungicidal activity against Pseudoperonospora cubensis, and the activity has been systematically studied as a function of molecular structure. The low activity of the ...