Copper (I) promoted acylation reactions. A transition metal mediated version of the Friedel-Crafts reaction

AP Kozikowski, A Ames

文献索引：Kozikowski, Alan P.; Ames, Anthony Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 860 - 862

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被引用次数: 75

摘要

CH3 (CH2) s- Toa DEU 2 0 40 inally initiated to achieve a new synthesis of 2-unsubstituted oxazoles. We had envisaged that selenol esters could replace acid chlorides in the assembly of these heterocycles from activated isonitriles, if these reactions were conducted in the presence of a soft metal ion showing a strong affinity for selenium. This process would thuvserve as a useful modification to the standard Schollkopf oxazole~ ynthesis.~ Our ...