Synthesis of (ϵ??13C??, ϵ??15N)??Enriched L??Lysine− Establishing Schemes for the Preparation of All Possible 13C and 15N Isotopomers of L??Lysine, L??Ornithine, and …

…, R Steen, J Raap, J Lugtenburg

文献索引：Siebum, Arjan H. G.; Tsang, Robert K. F.; Van Der Steen, Rob; Raap, Jan; Lugtenburg, Johan European Journal of Organic Chemistry, 2004 , # 21 p. 4391 - 4396

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被引用次数: 13

摘要

Abstract In this paper we describe a simple synthetic strategy that, with the right rational adaptation, gives direct access to any 13 C/15 N isotopomer of L-glutamate, L-ornithine, L- proline, L-lysine, and L-α amino adipic acid. This strategy also allows access to nonproteinogenic amino acids like L-citrulline in high yields and optical purity.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)