An approach to some spiro oxindole alkaloids through cycloaddition reactions of 3-methylideneindolin-2-one

…, RFC Brown, FW Eastwood, JM Horvath

文献索引：Bell, Stephanie E. V.; Brown, Roger F.C.; Eastwood, Frank W.; Horvath, Julianna M. Australian Journal of Chemistry, 2000 , vol. 53, # 3 p. 183 - 190

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被引用次数: 18

摘要

Abstract 3-Methylideneindolin-2-one (3-methylideneoxindole)(1) was prepared in 60–89% yield by flash vacuum pyrolysis of the acetate or methyl carbonate of 3-hydroxy-3- methylindolin-2-one, and was fully characterized, but application of the same procedure to 3- hydroxy-5-methoxyindolin-2-one did not give useful yields. Cycloaddition reactions of CH 2=+ NR–CH 2–and of the related ylide (25)(from 1-(trimethylsilylmethyl) piperidine-2- ...