Chiral polycyclic indoles are ubiquitous and important ring systems found in many bioactive alkaloids and pharmaceuticals.[1] As a result, extensive effort has been devoted to the development of efficient methods for their synthesis. Most approaches developed to date are based on the direct functionalization of the “privileged” indole core.[2] Representative strategies include asymmetric intramolecular alkylation of the C3, C2, or N1 positions of ...
