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Journal of Heterocyclic Chemistry

Reactions of o??aminonitriles with isocyanates. 1. A two??step synthesis of 2, 6??dihydroimidazo [1, 2??c] quinazolin??5??(3H) one

EP Papadopoulos

文献索引:Papadopoulos, Eleftherios Paul Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 6 p. 1553 - 1558

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被引用次数: 20

摘要

Abstract The reaction of anthranilonitrile with 2-chloroethyl isocyanate yields 2-[3-(2- chloroethyl) ureido] benzo-nitrile (6) which, upon heating, or treatment with base, undergoes a double cyclization to form 2, 6-dihydroimidazo [1, 2-c] quinazolin-5-(3H) one (8) in

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