Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The western subunit (fused bicyclic 16+15 membered ring) was synthesized by sequential intramolecular S N Ar reaction and the first 17-membered ring compound as model of the eastern subunit was obtained by an intramolecular Ni 0 mediated coupling reaction. ... Cookies are used by ...