Abstract Cis-3 and 3, 5-substituted pyrrolizidines can be prepared from β-enaminolactones. Substituted pyrrolidinoketones lead to these compounds by an amino reductive annelation with a low diastereomeric excess, but a best access to these azabicycles consists in preparing cis-2, 5-disubstituted pyrrolidines which are then transformed into the expected heterocycles.
