Design and synthesis of positional isomers of 1-alkyl-2-trifluoromethyl-5 or 6-substituted benzimidazoles and their antimicrobial activity

…, B Narsaiah, AR Reddy, D Lakshmi, B Sridhar

文献索引：Sathaiah; Ravi Kumar; Chandra Shekhar; Raju; Shanthan Rao; Narsaiah; Raghuram Reddy; Lakshmi; Sridhar Medicinal Chemistry Research, 2013 , vol. 22, # 3 p. 1229 - 1237

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被引用次数: 6

摘要

Abstract A series of novel positional isomers of 1-alkyl-2-trifluoromethyl benzimidazole derivatives 3a–j and 4a–j have been synthesized and screened for antibacterial activity against gram positive bacteria viz, Bacillus subtilis, Staphylococcus aureus and gram negative bacteria viz., Escherichia coli, Pseudomonas aeruginosa and antifungal activity against Candida albicans, Aspergillus niger, Rhizopus oryzae and Saccharomyces ...