Synthesis of N-benzyl-and N-phenyl-2-amino-4, 5-dihydrothiazoles and thioureas and evaluation as modulators of the isoforms of nitric oxide synthase

CLM Goodyer, EC Chinje, M Jaffar, IJ Stratford…

文献索引：Bioorganic and Medicinal Chemistry, , vol. 11, # 19 p. 4189 - 4206

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被引用次数: 43

摘要

... Bioorganic & Medicinal Chemistry. ... b MRC Experimental Oncology Laboratory, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road ... 8 Thus selective and potent inhibition of the isoforms of NOS is an important goal in medicinal chemistry. ...